Precious ginseng tablet candy Rg3

This product is made of high content ginsenoside 20 (R) - Rg3 and honeysuckle extract.

1、 Product advantages

1. High content of ginsenoside 20 (R) - Rg3

Each tablet of this product contains 25 mg of 20 (R) - Rg3, which is 6-8 times higher than other similar products (3-4 mg / tablet) in China. The high content of Rg3 can ensure the effective blood concentration in human body and play its biological activity. In order to achieve the effect of daily health care, 20 (R) - Rg3 should be taken at a dose of 30-40mg per day; in order to play the effect of rehabilitation treatment, 25-50mg per day should be taken. Therefore, taking 2-4 capsules of this product every day can meet the needs, which is incomparable to other competing products.

2. Gold compatibility of ginseng and honeysuckle extract

Ginseng can be used for invigorating vital energy, invigorating the spleen and benefiting the lung, promoting the body and nourishing blood, calming the mind and improving intelligence. It can be used for deficiency of the body, deficiency of the limbs, deficiency of the spleen and little food, deficiency of the lung, asthma and cough, injury of the body and thirst, internal heat and thirst, deficiency of Qi and blood, deficiency of the long-term illness, palpitation and insomnia, impotence and cold of the palace.

Functions of ginseng:

(1) It can improve the process of brain stimulation and inhibition, make it balance, improve the ability of brain and physical work, improve work efficiency, and have the effect of anti fatigue, nourishing and strengthening, and enhancing physical endurance;

(2) strong body immunity, has the function of anti arrhythmia and anti aging.

(3) Good memory, improve brain power, intelligence and adaptability;

(4) It can save blood pressure, strengthen heart muscle, relax vascular smooth muscle, accelerate blood flow, improve heart failure, improve arteriosclerosis, etc;

(5) It can promote the metabolism of glucose in liver, promote the secretion of insulin and regulate blood sugar;

(6) Enhance sexual function, sexual desire, and promote sperm growth and motility;

(7) Protein synthesis and regeneration of hepatocytes, regulating gastrointestinal function;

(8) Suitable for cancer patients, AIDS patients and so on.

Honeysuckle can not only disperse the wind heat, but also be good at clearing the blood toxin. It can be used in various kinds of heat diseases, such as body heat, rash, hair spot, heat toxin, carbuncle, sore throat and so on.

(1) Honeysuckle has the function of cooling blood and stopping dysentery. It has the effect of detoxifying dysentery, cooling blood and benefiting pharynx;

(2) Honeysuckle has the function of relieving heat and dispelling pathogenic factors. It has certain effect on the beginning of exogenous wind heat or febrile diseases, body heat and headache, restlessness and little sleep, dizziness and crimson tongue, dry throat and dry mouth, etc;

(3) The biological activity of chlorogenic acid contained in honeysuckle can promote human metabolism, regulate human function and improve immunity;

(4) Honeysuckle can reduce blood pressure, lower serum cholesterol, increase blood flow of coronary artery, prevent coronary heart disease and heart glue pain, inhibit the formation of cerebral thrombus, improve the tolerance of hypoxia free radicals, enhance memory, delay aging, improve microcirculation, remove the accumulation of peroxidized fat, promote metabolism, moisten and remove spots;

(5) Honeysuckle has bacteriostatic and bactericidal effects on pneumococcus, meningococci, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Shigella dysentery, Streptococcus mutans, and has inhibitory effects on influenza virus, orphan virus, herpes virus and Leptospira.

2、 Introduction of Ginsenoside Rg3

Ginsenoside Rg3 is a rare saponin produced by ginseng in the process of high-temperature processing (such as processing of Korean ginseng). When processing ginsenoside Rb1 with high content in total ginsenoside, it can be obtained by hydrolyzing and removing two hexoses. It is a tetracyclic triterpenoid panaxadiol saponin monomer, insoluble in water. Its chemical structure is shown in the figure below.

Molecular structure formula of Ginsenoside Rg3

In 1980, Kitagawa Xun, a famous Japanese natural medicine chemist, first extracted 20 (R) - Rg3 from red ginseng. Later, its isomer 20 (s) - Rg3 was also isolated and identified. They have similar pharmacological effects, but they are different in some details. For example, 20 (R) - Rg3 has stronger anticoagulant and anti epithelial stromal (EMT) effects, and 20 (s) - Rg3 has stronger anti cell proliferation effects.

At present, there are many chemical or biological methods for industrialized production of Rg3. Jilin Yatai Pharmaceutical Co., Ltd. is one of the first pharmaceutical companies in China to produce and sell Rg3 containing drugs. "Shenyi capsule" produced by the company is a kind of new Chinese medicine with 20 (R) - Rg3 as the main component. In 2000, it obtained the new drug certificate and production approval number issued by the State Drug Administration, and in 2003, it was officially produced and put on the market. According to the instructions, the main functions of Shenyi capsule are: cultivating yuan to strengthen the foundation and replenishing qi and blood. Combined with chemotherapy, it can improve the curative effect of primary lung cancer and liver cancer, improve the symptoms of qi deficiency of tumor patients, and improve the immune function of the body. In the past ten years, Shenyi capsule has been widely used as an auxiliary anti-tumor drug. In 2016, the sales volume of "Shenyi capsule" exceeded 500 million yuan for the first time; in 2017, "Shenyi capsule" entered the medical insurance drug catalog.

3、 Pharmacological action of Ginsenoside Rg3

1. Antitumor

(1) Antitumor effect in vitro

Many in vitro experiments at home and abroad have found that Rg3 has a broad-spectrum inhibitory effect on the proliferation of tumor cells. Including breast cancer MCF-7 cells, colon cancer HT29 cells, lung adenocarcinoma A549 cells, melanoma BI6 cells, retinoblastoma hxo-rb44 cells, bladder cancer EJ Cells, etc.

The mechanism of Rg3's antitumor effect in vitro mainly includes two aspects: ① by inhibiting the synthesis of nucleic acids and proteins related to mitosis of tumor cells, blocking the cell cycle of tumor cells, making them stay at the G0 / G1 phase; ② by regulating apoptosis related proteins Bax, Bcl-2, Caspase-3, etc., promoting the apoptosis of tumor cells.